EBM Resources

I’ve been teaching evidence-based medicine (EBM) at the University of Minnesota since 2004. This page contains EBM resources for our Family Medicine Clerkship students. Those visiting from outside the University of Minnesota should use the PubMed and Google Books links, where provided


Data Interpretation
Step 1: Is the difference real? (no major flaws, statistically significant)
Step 2: Does the difference matter to patients? (MCID, effect size)


C
Centre for Evidence-Based Medicine
Clinical Versus Statistical Prediction [textbook]

D
Diagnosis [PowerPoint]
Diagnosis: What Doctors Are Missing [essay]
Diagnostic Error
Disease-Oriented Outcomes (DOO) [see also POO]
DynaMed [vs. UpToDate — see Figure 1]

E
Effect size [see Cohen’s d]
Effect size [calculator]
Evidence-based medicine, alternatives to
Evidence-Based Medicine Toolkit
Evidence-Based Physical Diagnosis [textbook] (Google Books)

F
Funnel plot [publication bias]

G
Generally Recognized as Safe (GRAS)

H
Heterogeneity
How Doctors Think [book]
How Doctors Think [essay]

I
I2 (I-squared)
Intention-to-treat analyses (PubMed)

L
Level of Evidence (LOE) [required taxonomy]

M
Minimal clinically important difference (MCID) (PubMed)
Motivated reasoning

N
Negative Predictive Value (NPV; a/k/a Negative Predictive Power [NPP])
Network meta-analyses [see Figure 4] [and also here]
Non-inferiority studies [see Figure 1] (PubMed)
Number needed to treat (NNT) [calculator]

O
Observational studies (PubMed)

P
P-values (PubMed) (and Table 1 here)
Patient-Oriented Evidence that Matters (POEM)
Patient-Oriented Outcome (POO) [see also DOO]
Per-protocol analyses (PubMed)
Placebo effect, likely overestimated
Positive Predictive Value (PPV; a/k/a Positive Predictive Power [PPP])
Power, a priori [calculator]
Power, post-hoc [calculator]
Publication bias: see Funnel plot

R
Rational Clinical Examination [textbook] (Google Books)
Reliable evidence

S
Statistics Notes [long-running feature in BMJhighly recommend!]
Strength of Recommendation Taxonomy (SORT) [required taxonomy] (and Figure 1 here)

T
Test validation summary (PubMed) [PPV and NPV for any base rate]
Therapy [PowerPoint]
Type I and Type II errors (PubMed)

U
United States Preventative Services Task Force (USPSTF)
UpToDate [vs. DynaMed — see Figure 1]
Users’ Guides to the Medical Literature [textbook] (Google Books)

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